Major cardiac risk in aspirin-resistant patients
From Australian Doctor, 21 January 2008:
BMJ Aspirin resistance, thought to affect up to one-third of patients, is associated with significantly increased cardiovascular morbidity, a comprehensive meta-analysis suggests.
The research, which analysed 20 studies including 2930 patients with cardiovascular disease, found aspirin-resistant patients had an almost sixfold increase in risk of death, were almost four times more likely to experience a cardiovascular event, and were at more than four times greater risk of acute coronary syndrome compared with non-resistant patients. Read more.
Labels: aspirin, Australian Doctor, British Medical Journal, cardiovascular disease


1 Comments:
In a study that explores the prevalence of aspirin resistance in chronic renal failure, "aspirin resistance was detected in 53 patients undergoing hemodialysis, 32 patients with stage 3-4 chronic kidney disease and 22 controls." It concluded that "patients with CRF have higher frequency of aspirin resistance, which might increase the risk of cardiovascular morbidity and mortality."
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